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Moumoujus

HUMAN TOOTH PULP STEM CELL CONDITIONED MEDIA EXTRACT.

Insufficient Data / HUMECTANT, SKIN CONDITIONING

This advanced ingredient, often referred to as hDPSC-CM, is a secretome derived from human tooth pulp stem cells. It is rich in an array of bioactive substances, including essential growth factors, cytokines, and exosomes, that act as cellular messengers to promote regeneration and repair processes within the skin.

Summary

Cell activation Tissue repair Tissue regeneration Wound healing Angiogenesis Antioxidant support Immunomodulation Anti-aging

Science

Mechanism of Action

Human Tooth Pulp Stem Cell Conditioned Media Extract operates by delivering a complex profile of intercellular messengers, such as Nerve Growth Factor (NGF), Vascular Endothelial Growth Factor (VEGF), and Hepatocyte Growth Factor (HGF), along with cytokines and exosomes. These components support cellular activation, enhance tissue repair, and facilitate regeneration. The extract stimulates the proliferation, migration, and survival of various cell types, demonstrating properties linked to wound healing, angiogenesis, and protection against oxidative stress-induced cellular damage. It also exhibits immunomodulatory effects, influencing immune cell differentiation and suppressing inflammatory responses.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 7.2 – 7.8
0 7 14

Stability

Due to its complex biological nature, this conditioned medium requires precise storage conditions. It is unstable at room temperature and must be stored at 2-8°C, shaded from light, for up to 6 months, or at -80°C for longer durations. Aseptic handling is critical during formulation to prevent contamination, and the concentration of its active components can fluctuate, impacting overall stability.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) has not specifically reviewed HUMAN TOOTH PULP STEM CELL CONDITIONED MEDIA EXTRACT for cosmetic applications. While some studies on human dental pulp stem cells in regenerative medicine report safety, these findings are often for cell transplantation rather than topical use and can show conflicting feedback. Although generally considered non-irritating, a comprehensive review of research for cosmetic application is essential to ascertain its full safety profile.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

This ingredient presents a highly promising biological mechanism for skin regeneration and repair; however, specific clinical efficacy data for topical cosmetic applications and comprehensive safety reviews are currently lacking, warranting further research.

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