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Moumoujus

HUMAN PLACENTAL LIPIDS.

Avoid CAS - / HAIR CONDITIONING, SKIN CONDITIONING

Human Placental Lipids are a complex mixture of fatty compounds derived from the human placenta. They are fundamental for maintaining skin barrier integrity and facilitating cellular communication, contributing to the structural and functional health of the epidermis.

Summary

Skin Barrier Reinforcement Intercellular Signaling Cellular Membrane Synthesis Skin Elasticity Enhancement Hydration Support Cell Turnover Promotion Antioxidant Activity Anti-inflammatory Effects

Science

Mechanism of Action

As integral components of cellular plasma membranes, Human Placental Lipids, including phospholipids and triacylglycerols, are vital for skin barrier function and intercellular signaling. While isolated lipid benefits are focused on these roles, they are typically found within broader placenta extracts. These extracts, encompassing a wide array of proteins, peptides, growth factors, and vitamins alongside lipids, are collectively associated with stimulating collagen and elastin synthesis, enhancing skin elasticity, improving hydration, and promoting accelerated cell turnover. Additionally, the broader extract is recognized for its antioxidant, anti-inflammatory, and skin repair properties, aiding in the reduction of hyperpigmentation and supporting wound healing processes.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Commonly dusted

Claims attributed to 'Human Placental Lipids' often stem from research on complete placenta extracts, which contain numerous other bioactive substances like growth factors and peptides. Focusing solely on lipids might misrepresent the full spectrum of benefits consumers associate with the broader ingredient, as noted by the FDA regarding potential for misleading labeling.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Conflicts

  • Prohibited for use in cosmetic products in the European Union due to concerns regarding transmissible diseases from human-derived materials.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel deemed existing safety data insufficient, specifically requesting further studies on skin sensitization, reproductive/developmental toxicity, photosensitization, genotoxicity, and ocular toxicity. Furthermore, Human Placental Lipids are explicitly prohibited in cosmetic products within the European Union due to significant concerns regarding the potential transmission of human spongiform encephalopathies and viral diseases (e.g., HIV). The FDA also cautions against identifying hormone-depleted placenta-derived ingredients as 'placenta extract' if they lack associated biological activities, to prevent consumer misleading.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Due to insufficient safety data from the CIR, a full prohibition in the European Union, and a lack of specific clinical efficacy for isolated human placental lipids, this ingredient carries significant regulatory and safety concerns.

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