Science
Mechanism of Action
The mechanism is theorized to involve the diverse cellular components within the lysate, such as growth factors and proteins, which may interact with skin cells to support barrier function and hydration. These components are thought to leverage the regenerative capacity associated with the iPSC origin to contribute to overall skin health.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
While optimal pH for cosmetic formulations is not specified, a related human PBMC lysate is prepared in Tris-HCl buffer at pH 6.8 and stored at -20°C. To maintain stability and component integrity, avoiding repeated freeze/thaw cycles is recommended.
Safety
Safety Profile
This ingredient has not undergone review by the Cosmetic Ingredient Review (CIR) or the Scientific Committee on Consumer Safety (SCCS). The U.S. FDA's regulation of iPSCs is primarily for therapeutic applications, not for cosmetic ingredient approval. Rigorous safety testing for iPSC lines for clinical use (e.g., genetic stability, sterility, tumorigenicity) applies to cell therapy, not directly to cosmetic product safety.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Due to a lack of clinical studies and specific cosmetic safety reviews from regulatory bodies, there is currently insufficient data to definitively assess the efficacy and safety of this ingredient for skincare applications.
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References
Sources