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Moumoujus

HUMAN CORONAVIRUS OLIGOPEPTIDE-1 SP.

Questionable / SKIN PROTECTING

This peptide, commonly known as Oligopeptide-1 or EGF, promotes epidermal cell growth and helps to slow the thinning of aging skin. It accelerates skin cell renewal and wound healing, while boosting collagen, elastin, and hyaluronic acid synthesis for smoother, plumper skin.

Summary

Skin-conditioning Cell-communicating ingredient Anti-aging Wound healing Skin renewal Firming Smoothing Soothing Collagen boosting Elastin boosting Hyaluronic acid boosting Redness reduction Inflammation reduction

Science

Mechanism of Action

Oligopeptide-1 functions as a cell-communicating agent, stimulating cell growth, proliferation, healing, and differentiation. It also strengthens the skin's barrier, reduces redness, and soothes inflammation to restore skin balance.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Journal of drugs in dermatology: JDD 11.5 (2012): 613-620.
  2. 02 Cutaneous and Ocular Toxicology 42(9):1-8 (2023)

Transparency

Dusting Analysis

Not commonly dusted

While authorized for generalized cosmetic use, a critical review questions the scientific basis of its preclinical bioactivity and highlights unknown long-term risks, raising doubts about its overall efficacy.

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 8
0 7 14

Stability

Oligopeptide-1 is highly pH-sensitive, requiring a pH range of 5.0-8.0 for optimal stability and must be protected from microbial contamination during product processing.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Low

Generally well-tolerated, with CIR status as 'insufficient data' and unknown long-term risks noted by a critical review. The 'HUMAN CORONAVIRUS' prefix is not typically associated with its cosmetic function, while 'SP' may refer to a plant-derived peptide.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

Despite some positive studies and general authorization, a significant lack of proven preclinical bioactivity and unknown long-term risks make the overall efficacy and safety of this ingredient questionable.

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