Science
Mechanism of Action
Hornet silk proteins, particularly Vssilk1 and Vssilk2, possess a net positive charge under physiological conditions. This positive charge is hypothesized to facilitate significantly higher cell adhesion activity, suggesting a role in supporting cellular attachment and interaction at a biomaterial level.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This protein requires specific conditions for dissolution; an aqueous solution is achievable at pH values exceeding 9.2. It also dissolves in high-concentration salt solutions such as 4.5 M calcium chloride (CaCl2) at 20°C, or 7.2 M to 9.0 M lithium bromide (LiBr) at 25°C. For non-aqueous systems, it shows solubility in hexafluoroisopropyl alcohol (HFIP) at 25°C without molecular degradation. Solubility is temperature-sensitive.
Safety
Safety Profile
Comprehensive safety assessments by regulatory bodies such as CIR, SCCS, or FDA for hornet silk as a cosmetic ingredient are not currently available. A notable skincare authority identifies it as a novel ingredient lacking established benefits or safety ratings.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Current data regarding hornet silk is limited to its biomaterial properties and cell culture potential, lacking sufficient evidence for cosmetic efficacy or safety.
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References
Sources