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HORDEUM VULGARE EXTRACT.

Insufficient Data CAS 85251-64-5 / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Hordeum Vulgare Extract, derived from barley, is a versatile ingredient prized for its multi-faceted benefits, including soothing irritation, enhancing skin repair, and providing robust antioxidant protection. It works to improve skin's resilience, hydration, and overall vitality, suitable for a wide range of skin types.

Summary

Skin conditioning Soothing Anti-inflammatory Antioxidant Regeneration-boosting Barrier-improving Anti-aging Hydrating Nourishing Emollient Humectant

Science

Mechanism of Action

This extract precisely modulates gene expression to support skin soothing, revitalization, and repair, leading to anti-inflammatory and barrier-strengthening outcomes. It actively reduces accessory protein expression, thereby limiting IL-1 receptor activation and consequently mitigating inflammation, discomfort, and pain. Furthermore, it stimulates extracellular matrix (ECM) production, crucial for repair and targeting visible signs of aging like fine lines, while also contributing a rich profile of antioxidants, vitamins, and minerals to hydrate and nourish the skin, bolstering elasticity and defending against environmental stressors.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Demonstrated to be non-irritating in an eye cream for contact and non-contact lens wearers, including individuals with self-perceived sensitive eyes, and showed no irritation in a 48-hour patch test.
  2. 02 A preparation featuring Hordeum Vulgare seed extract achieved a significant average reduction in skin redness, measuring 70.59% by clinician assessment and 89.91% via instrumental measurement.
  3. 03 At this concentration, Hordeum vulgare L. extracts effectively increased human skin fibroblast viability/proliferation by 24% after exposure to UVB radiation, indicating potential for repair and protection.
  4. 04 Ethanol and methanol extracts derived from barley leaves exhibited strong antioxidant capacity, with DPPH scavenging rates of approximately 80.3% and 79.5% respectively.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 3.5 – 4.7
0 7 14

Stability

Aqueous extracts are common, and preparations are stable within a pH range of 3.5 to 4.7. It can be prepared in water and glycerin. Notably, barley grass extract may impart a green pigmentation to formulations.

Conflicts

  • Individuals with gluten sensitivity should avoid this ingredient due to potential for allergic reactions, including reported contact urticaria.

Safety

Safety Profile

CIR Status
Insufficient data
Max tested
1.5%
Sensitization risk Moderate

As of November 2021, the CIR Expert Panel deemed data insufficient to determine the safety of the general 'Hordeum Vulgare Extract' (whole plant extract) in cosmetics, requesting further dermal toxicity data. However, 'Hordeum Vulgare Seed Extract' was concluded to be safe. The highest reported concentration in cosmetic products is 1.5% in leave-on body and hand care. Barley is a source of gluten, and contact urticaria has been documented in gluten-sensitive individuals, indicating a specific allergic risk. Malt extract from Hordeum vulgare L. holds a 'Generally Recognized As Safe' (GRAS) status by the US FDA for animal feeds.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While Hordeum Vulgare Extract demonstrates valuable soothing, anti-aging, and antioxidant properties, the CIR Expert Panel has determined insufficient safety data for the general 'whole plant extract' form, necessitating careful consideration and formulation.

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