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Moumoujus

HIPPURIC ACID.

Avoid CAS 495-69-2 / HAIR CONDITIONING

Hippuric Acid is an organic acid whose properties are explored for potential utility in skincare, specifically regarding skin hydration and barrier function. However, its use is severely limited by significant safety concerns and an absence of comprehensive clinical data.

Summary

Skin conditioning

Science

Mechanism of Action

Research suggests Hippuric Acid may play a role in supporting the skin's hydration mechanisms and reinforcing the skin barrier. Conversely, excessive concentrations have been implicated in contributing to oxidative stress within cutaneous tissues.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Conflicts

  • hot caustic alkalis (strong bases)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

Hippuric Acid is classified with GHS hazard statements indicating it causes skin irritation (Category 2) and serious eye damage (Category 1). It is also noted as harmful if swallowed and may cause respiratory irritation. Despite some conflicting reports, it is considered a hazardous substance under OSHA 29 CFR 1910.1200.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Given the absence of definitive clinical efficacy data, unreviewed safety status by CIR, and clear GHS hazard classifications for skin and eye irritation, Hippuric Acid is deemed unsuitable for inclusion in precision skincare formulations.

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