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HIPPOPHAE RHAMNOIDES OIL.

Valuable CAS 225234-03-7 / 90106-68-6 / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Hippophae Rhamnoides Oil, derived from the sea buckthorn plant, is a nutrient-rich botanical oil prized for its multifaceted skin benefits. It acts as a potent antioxidant, soothes inflammation, and strengthens the skin's natural barrier function.

Summary

Antioxidant Emollient Skin-softening Soothing Anti-inflammatory Skin barrier support Wound healing

Science

Mechanism of Action

This oil works through several mechanisms: it provides significant antioxidant protection by neutralizing free radicals and preventing UV-induced oxidative stress and lipid metabolism disturbances. It supports skin barrier integrity by mimicking natural lipids via omega-7 fatty acids (palmitoleic acid) and forming a protective occlusion with palmitic and stearic acids. Hippophae Rhamnoides Oil also promotes epidermal regeneration and wound healing by encouraging keratinocyte and fibroblast proliferation and collagen synthesis. Furthermore, it exhibits anti-inflammatory effects, reducing the severity of dermatitis, and supports hydration by up-regulating aquaporins 3 and hyaluronan synthetases 2 expressions.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro studies at 500 ng/mL demonstrated prevention of UV-induced redox imbalance and disruptions in lipid metabolism in human keratinocytes and fibroblasts.
  2. 02 Topical application in a mouse model with atopic dermatitis-like lesions significantly ameliorated dermatitis severity, decreased epidermal thickness, and inhibited mast cell infiltration by suppressing NF-κB and STAT1 activation.
  3. 03 Clinical application showed an increase in healing rates, reducing epithelialization time from 24.8 days to 16.3 days compared to control treatments.

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
High concentrations%

While generally well-tolerated, Hippophae Rhamnoides Oil is not typically 'dusted' due to lack of efficacy. However, high, undiluted concentrations can lead to mild comedogenicity, temporary skin staining, and may be unsuitable for Malassezia folliculitis due to its rich fatty acid content. These issues arise from concentration rather than inherent ineffectiveness.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

For optimal stability and longevity, maintain limited contact with oxygen during storage.

Conflicts

  • May be mildly comedogenic in high concentrations.
  • Undiluted application can temporarily stain skin orange.
  • May not be suitable for Malassezia folliculitis (fungal acne) due to its rich fatty acid profile.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) deems Hippophae Rhamnoides Oil safe as used, implying safety within typical cosmetic concentrations. It is generally well-tolerated by most skin types, including sensitive skin, with a low risk of allergies. However, high concentrations may exhibit mild comedogenic properties and can temporarily impart an orange tint to the skin. Dilution with a carrier oil is recommended for facial application, along with a patch test.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Hippophae Rhamnoides Oil is a highly valuable ingredient offering significant antioxidant, anti-inflammatory, and barrier-supporting benefits across all skin types, with generally low irritancy and comedogenicity when properly formulated.

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