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HEXYLDODECYL SALICYLATE.

Valuable CAS 220778-06-3 / HAIR CONDITIONING, SKIN CONDITIONING, SOLVENT

Hexyldodecyl Salicylate serves as a versatile skin and hair conditioning agent, contributing emollient properties and acting as a solvent in formulations. As an ester of salicylic acid, it also offers the potential for mild desmolytic or keratolytic action upon hydrolysis, promoting gentle exfoliation.

Emollient Solvent Skin conditioning Hair conditioning

Science

This ingredient primarily functions as a skin and hair conditioning agent, enhancing texture and feel. Its role as a solvent facilitates the dissolution of other compounds within a formulation. Given its structure as a salicylic acid ester, Hexyldodecyl Salicylate can, upon hydrolysis, release salicylic acid, potentially contributing to mild desmolytic or keratolytic effects by disrupting cellular junctions and supporting skin exfoliation.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

As an ester, Hexyldodecyl Salicylate is susceptible to hydrolysis, particularly when exposed to extreme pH conditions. Salicylates generally exhibit enhanced stability in acidic environments, with degradation kinetics accelerating at higher pH values.

Conflicts

  • Acids (potential precipitation of salicylic acid if hydrolysis occurs)
  • Ferric salts (relevant for soluble salicylates)
  • Alkali bicarbonates (relevant for soluble salicylates)

Safety

CIR Status
Safe with restrictions
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Panel has deemed Hexyldodecyl Salicylate safe for use, provided it is formulated to prevent skin irritation. Additionally, formulations must either avoid increasing skin's sun sensitivity, or if such an increase is anticipated, product directions must explicitly advise daily sun protection.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Hexyldodecyl Salicylate is a valuable ingredient for its emollient, solvent, and conditioning properties, with potential for mild exfoliation, requiring careful formulation to ensure safety and stability.


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