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HEXYL ACETATE.

Optional CAS 142-92-7 / FLAVOURING, FRAGRANCE, PERFUMING

A naturally occurring ester, Hexyl Acetate primarily serves as a perfuming and masking agent in skincare formulations, enhancing the sensory experience. Beyond its aromatic contributions, it demonstrates potential protease activity and broad-spectrum antimicrobial properties.

flavouring masking perfuming protease_activity antimicrobial_activity

Science

Hexyl Acetate exhibits protease activity, which may involve the formation of hydrogen bonds with amino groups on proteins, potentially leading to targeted protein breakdown. Additionally, it possesses inherent antimicrobial capabilities.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

No data available to suggest Hexyl Acetate is commonly 'dusted' or associated with misleading efficacy claims.


The Formula

Solubility
Oil
Optimal pH 6 – 9
0 7 14

Stability

Hexyl Acetate demonstrates good stability within a pH range of 6 to 9. Stability is compromised in strongly acidic (pH 2) and strongly alkaline (pH 11) environments, where hydrolysis in aqueous systems may occur, potentially requiring stabilization measures.

Conflicts

  • High pH formulations (potential hydrolysis)
  • Strongly acidic formulations

Safety

CIR Status
Safe as used
Max tested
4%
Sensitization risk Low

The Research Institute for Fragrance Materials (RIFM) has concluded that Hexyl Acetate does not pose a concern for skin sensitization based on current data. It holds a Generally Recognized as Safe (GRAS) status by FEMA for food flavoring. EWG's Skin Deep database indicates low concerns for endocrine disruption, non-reproductive organ system toxicity, and irritation to skin, eyes, or lungs.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Optional

Primarily valued for its sensory attributes in formulations, Hexyl Acetate is a generally safe ingredient with demonstrated antimicrobial properties and potential protease activity.


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References