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Moumoujus

HEXAMETHYLENE BIS-HYDROXYSTEARAMIDE.

Insufficient Data CAS 55349-01-4 / HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING

Hexamethylene Bis-Hydroxystearamide is a stable solid surfactant prized for its dual role as a skin conditioning agent and humectant. It effectively forms a protective film on the skin's surface, which helps to improve its texture and significantly reduce water loss, making it particularly beneficial for dry skin types.

Summary

Skin conditioning agent Humectant Emollient Occlusive Thickener Gelling agent

Science

Mechanism of Action

This ingredient operates by forming a stable, protective film on the skin, attributable to its structure as a solid surfactant containing long-chain fatty acid and amide groups. This film acts as an emollient and occlusive barrier, improving the skin's surface properties and indirectly functioning as a humectant by supporting the natural skin barrier and minimizing transepidermal water loss.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Hexamethylene Bis-Hydroxystearamide is a remarkably stable solid surfactant, demonstrating resilience to both heat and various chemical substances. For optimal incorporation into formulations, it requires heating within a solvent to dissolve, followed by careful cooling with continuous stirring to precipitate and form a consistent paste.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically reviewed Hexamethylene Bis-Hydroxystearamide, though it is registered with the FDA Substance Registration System (UNII: 2FS31BFC0F). While 66.3% of aggregated GHS reports indicate it does not meet hazard criteria, a notable 25.2% of reports suggest a potential to 'cause an allergic skin reaction' (H317). Furthermore, 33.7% of reports indicate it 'May cause long lasting harmful effects to aquatic life' (H413).

Your Skin

Skin Compatibility

No Normal
Yes Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While Hexamethylene Bis-Hydroxystearamide shows promise for enhancing skin conditioning and barrier function, particularly for dry skin, the absence of dedicated clinical studies and CIR review, combined with a 25.2% reported risk of allergic skin reactions, highlights a need for more comprehensive safety and efficacy data before a definitive assessment.

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