Science
Mechanism of Action
This ingredient functions by imparting a pleasant scent to formulations and the skin, acting as a fragrance compound. It additionally serves as a masking agent to diminish or neutralize product odors. Furthermore, Hexadecanolactone is reported to possess emollient qualities, assisting in skin hydration and smoothing by forming a barrier that curtails transepidermal water loss.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Hexadecanolactone exhibits stability under typical conditions but is combustible. For optimal preservation, it should be stored in a cool, dry environment within tightly sealed containers, shielded from exposure to heat and light.
Conflicts
- strong oxidizing agents
Safety
Safety Profile
Hexadecanolactone has not been specifically evaluated by the CIR Expert Panel. However, the SCCS has assessed it, resulting in its inclusion in Annex III of the EC Cosmetics Regulation, indicating it is subject to restriction or express approval. It is classified as an established contact allergen in humans. Under the Cosmetic Fragrance and Flavor Ingredient Right to Know Act of 2020, its presence must be reported at concentrations of 0.01% (100 ppm) or higher in rinse-off products, and 0.001% (10 ppm) or higher in leave-on products. A RIFM safety assessment indicates no genotoxic or phototoxic/photoallergenic concerns, with a No Expected Sensitization Induction Level (NESIL) of 5500 μg/cm2 for skin sensitization. FDA status is not specifically detailed beyond general cosmetic regulations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Despite its emollient properties and fragrance utility, Hexadecanolactone is classified as an established human contact allergen, making it unsuitable for precision skincare formulations.
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