Science
Mechanism of Action
This peptide mimics laminin-5, a crucial molecule in the dermal-epidermal junction, improving its function. It stimulates epidermal proteins like integrins and keratins for barrier support and boosts collagen I and III synthesis, along with fibronectin for wound healing and cell adhesion.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Manufacturer studies show Heptapeptide-8 improves skin tonicity, smoothness, and supports cellular regeneration over 21 days.
Transparency
Dusting Analysis
Peptides are potent ingredients typically effective at low concentrations, making dusting less common than with other ingredient types.
The Formula
Formulation
Stability
Recommended for addition to emulsions during the cool-down phase, below 40°C.
Safety
Safety Profile
This ingredient has not been specifically reviewed by CIR, SCCS, or FDA for safety. Information regarding similar but distinct peptides (e.g., Acetyl Hexapeptide-8) indicates different safety profiles.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Heptapeptide-8 shows promising skin-rejuvenating benefits based on manufacturer studies, despite limited independent safety and compatibility data.
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References
Sources