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Moumoujus

HEPTAPEPTIDE-45.

Insufficient Data / ASTRINGENT, BLEACHING, HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Heptapeptide-45 is a signaling peptide ingredient intended to support the skin's inherent repair processes. Research on a specific heptapeptide, DEETGEF, demonstrates potential for protecting the skin from UV-induced DNA damage and stimulating crucial cell-protecting enzymes.

Summary

Signaling peptide Astringent Bleaching Humectant Skin-conditioning agent Emollient Antioxidant support DNA protection

Science

Mechanism of Action

As a signaling peptide, Heptapeptide-45 is theorized to interact with skin cells, thereby activating the skin's endogenous repair mechanisms. A particular heptapeptide, DEETGEF, has been shown to stimulate vital cell-protecting enzymes such as NQO1, HMOX1, and PRDX1, providing protection against DNA damage induced by UV irradiation. It also exhibits cosmetic attributes including astringent, humectant, and skin-conditioning effects.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

0.014%

Key findings

  1. 01 20% decrease in DNA damage, stimulation of cell-protecting enzymes, dose-dependent UV protection.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

Specific stability characteristics and optimal pH range for HEPTAPEPTIDE-45 are currently unknown. Peptides generally necessitate careful formulation to ensure stability, particularly concerning pH sensitivity.

Synergies

  • Vitamin B3 (Niacinamide)
  • Vitamin B5 (Panthenol)
  • Vitamin E (Tocopherol)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

HEPTAPEPTIDE-45 lacks specific safety assessments from major regulatory bodies such as CIR, SCCS, or FDA. While peptides, in general, are often considered to have a low toxicity profile, specific safety data for this particular ingredient remains unavailable.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While a specific heptapeptide (DEETGEF) shows promising capabilities in cellular protection and DNA damage reduction at 0.014% concentration, comprehensive direct research on HEPTAPEPTIDE-45 is insufficient to fully establish its efficacy and precise applications in skincare.

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