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Moumoujus

HC YELLOW NO. 7.

Insufficient Data CAS 104226-21-3 / HAIR DYEING

HC Yellow No. 7 is an organic colorant primarily utilized in hair care products to impart a yellow hue. While effective in its dyeing function for hair, comprehensive safety data, particularly for dermal application, has been deemed insufficient for a thorough risk assessment by regulatory bodies.

Summary

Hair Dyeing

Science

Mechanism of Action

This ingredient functions by directly depositing color molecules onto the hair shaft, facilitating a temporary or semi-permanent yellow coloration. Its mechanism of action is specific to keratin fibers and is not associated with direct physiological effects on skin.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

HC Yellow No. 7 is a hair dyeing agent and is not typically formulated or 'dusted' into precision skincare products for direct skin benefits.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This compound exhibits implied chemical sensitivity to both light and moisture. While its stability within typical hair dye formulations is not explicitly reported, tests of the raw material in specified dosage forms (e.g., 0.5% CMC, 0.5% MC, DMSO, and DMF) demonstrated satisfactory stability over a 4-hour period at room temperature when protected from light and maintained under an inert gas atmosphere.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

In 2010, the Scientific Committee on Consumer Safety (SCCS) concluded that the information submitted was inadequate to assess the safe use of HC Yellow No. 7, requiring more data on analytical properties, purity, stability, and sensitivity to light and moisture. Animal studies on rabbit skin showed no irritation at 500 mg; however, undiluted HC Yellow No. 7 was observed to be slightly irritating to rabbit eyes.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Due to inadequate safety data for skin applications as assessed by regulatory bodies and its primary function being limited to hair dyeing, HC Yellow No. 7 is not recommended for precision skincare formulations.

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References

Sources