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Moumoujus

HC RED NO. 13.

Avoid CAS 94158-13-1 / HAIR DYEING

HC Red No. 13 is a synthetic organic direct dye primarily utilized in hair coloration, imparting a red hue without requiring an oxidative reaction. While its primary application is for hair, research indicates potential for cutaneous absorption upon application to skin.

Summary

Hair Colorant

Science

Mechanism of Action

As a direct hair dye, HC Red No. 13 functions by adhering to the hair surface or slightly diffusing into the hair cortex to impart color. Its mechanism is not associated with any active benefit for skin; however, in vitro studies confirm its ability to be absorbed through the skin.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

HC Red No. 13 is primarily used as a hair dye and is not typically incorporated as a 'dusted' active ingredient in skincare formulations, therefore dusting analysis is not applicable.

The Formula

Formulation

Solubility
Water
Optimal pH 6 – 9
0 7 14

Stability

Requires precise pH control for optimal color stability, typically managed with a buffer system. It demonstrates high stability (98%) in physiological receptor fluid at pH 6.8 over 3 days, and good stability in vehicle for up to 7 days. Recovery rates remained above 90% in oxidative conditions with 6% hydrogen peroxide over 45 minutes, indicating robust stability.

Conflicts

  • Nitrosating substances (requiring nitrosamine content to be below 50 ppb)

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Moderate

The Scientific Committee on Consumer Safety (SCCS) identifies HC Red No. 13 as a moderate skin sensitiser, with an estimated EC3 of 8.2% indicating potential for sensitization. An in vitro study confirmed cutaneous absorption of the dye from a typical hair dye formulation. SCCS considers it safe for hair dye applications at maximum on-head concentrations of 2.5% in non-oxidative and 1.25% in oxidative formulations; however, these limits are for hair, not direct leave-on skin use. The Cosmetic Ingredient Review (CIR) has insufficient data for a comprehensive safety assessment, and it is not explicitly listed by the FDA as an approved cosmetic color additive in the provided summary.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

As a moderate skin sensitiser with documented dermal absorption and no identified benefits for skin, HC Red No. 13 should be avoided in precision skincare formulations.

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