Science
Mechanism of Action
For skin, HC Red No. 11 has no described mechanism of action for providing beneficial effects. Its function is primarily limited to hair coloring, where it adheres to the hair surface or penetrates the hair shaft.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
HC Red No. 11 is primarily a colorant for hair and lacks a described mechanism of action or demonstrated efficacy for skin. Therefore, it is not considered an active ingredient for 'dusting' in precision skincare formulations.
The Formula
Formulation
Stability
A mixture containing HC Red No. 10 and No. 11 demonstrated stability for 167 hours in phosphate buffered saline and 286 hours in soap solution. No specific optimal pH range was provided.
Conflicts
- N-nitrosating agents (nitrosamine content should be limited to <50 ppb if used together)
Safety
Safety Profile
The SCCS concluded that HC Red No. 11, when combined with HC Red No. 10, is safe for consumer health in hair dye formulations at maximum on-head concentrations of 1.0% (oxidative) and 2.0% (non-oxidative). Margins of Safety (MOS) were calculated at 900 (non-oxidative) and 1030 (oxidative), both considered safe (>100). A mixture containing 32.6% HC Red No. 11 was found not to be sensitizing to skin. It is listed in Annex III of the EC Cosmetics Regulation with certain restrictions. FDA status is not explicitly available for this specific chemical, with 'Red Dye #3' referring to a different compound.
Your Skin
Skin Compatibility
Our Assessment
Verdict
HC Red No. 11 is primarily a hair dye with no established mechanism of action or demonstrated clinical efficacy for skin, rendering its inclusion in precision skincare formulations for active benefits unsupported.
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References
Sources