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GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE.

Valuable CAS 65497-29-2 / ANTISTATIC, FILM FORMING, SKIN CONDITIONING, VISCOSITY CONTROLLING

Guar Hydroxypropyltrimonium Chloride is a positively charged, water-soluble polysaccharide derived from guar gum, renowned for its multifunctional benefits in skincare and haircare formulations. It primarily acts as a conditioning agent and film-former, enhancing texture and moisture retention.

antistatic hair conditioning skin conditioning film-forming moisture-trapping hydrating lubricity enhancing viscosity controlling

Science

This ingredient functions by utilizing its cationic (positively charged) nature. Its trimethylammonium groups are attracted electrostatically to the negatively charged surfaces of both the skin and damaged keratin fibers in hair. This interaction results in the formation of a thin, positively charged film, which effectively conditions, detangles, and reduces static in hair without imparting heaviness. On the skin, it forms a protective film that helps to prevent moisture loss, promoting hydration for a softer, smoother feel. Additionally, it improves product lubricity for easier application and acts as a viscosity controlling agent, potentially aiding in the delivery of other active or hydrophobic ingredients.


Research

Medium confidence
Effective range 0.1–0.5%
Optimal

0.1%

Key findings

  1. 01 Delivers superior conditioning and thickening effects in both hair and skin products, improving hair's wet and dry combability while reducing irritation during washing and providing a desirable slip and comfortable skin feel.
  2. 02 Demonstrated utility as a polymeric film-forming material, with concentrations up to 6% explored for specific film applications requiring intact detachment.

Transparency

Not commonly dusted

No specific data on dusting thresholds or red flag percentages were found in the available research.


The Formula

Solubility
Water
Optimal pH 3.5 – 6
0 7 14

Stability

Guar Hydroxypropyltrimonium Chloride readily dissolves in water at room temperature when the pH is adjusted between 5.5 and 6.0. For maximal viscosity development, it is typically dispersed in water, then acidified to a pH between 3.5 and 5.0, or pH 6 with citric acid for rapid thickening. It exhibits good compatibility with most anionic and amphoteric surfactants and remains unaffected by electrolytes. This ingredient contributes positively to a formulation's viscosity, overall stability, and emulsion stability.

Synergies

  • Compatible with most anionic and amphoteric surfactants.

Safety

CIR Status
Safe as used
Max tested
1%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has confirmed the safety of Guar Hydroxypropyltrimonium Chloride for its intended use in cosmetic and personal care products, deeming it non-irritating, non-sensitizing, and biodegradable. The FDA recognizes its parent compound, Guar Gum, as Generally Recognized As Safe (GRAS) for direct food use. While generally safe below 1% concentration, formulations exceeding 1% may pose a minimal to substantial irritation risk, particularly for sensitive skin, and thus warrant patch testing.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

Guar Hydroxypropyltrimonium Chloride is a valuable, safe, and versatile cationic polymer that significantly enhances the conditioning, hydration, and sensory experience of both skin and hair care formulations, while also contributing to product stability.


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