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GUANIDINE CARBONATE.

Valuable CAS 593-85-1 / BUFFERING, SKIN CONDITIONING

Guanidine Carbonate functions as a robust alkaline compound, essential for precise pH regulation and buffering in skincare formulations. It also offers mild exfoliating and skin conditioning properties, aiming to refine skin texture for a smoother finish.

pH regulator Buffering agent Mild exfoliant Skin conditioning agent

Science

This ingredient operates as a strong base, primarily adjusting and stabilizing the pH of a formulation. When applied to the skin, its alkaline nature contributes to a mild exfoliating effect, promoting cellular turnover, and acts as a conditioning agent to enhance skin texture, resulting in a soft and smooth feel.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

No data available suggests Guanidine Carbonate is commonly associated with dusting issues in cosmetic formulations.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Guanidine Carbonate is a strong base with a pKa of 12.5 at 20°C, forming solutions with a high pH (e.g., 4% solution at pH 11.4). Its strong alkaline nature ensures stability in high pH environments.

Conflicts

  • strong acids

Safety

CIR Status
Safe with restrictions
Sensitization risk Moderate

The CIR Expert Panel deems carbonate salts, including Guanidine Carbonate, safe in cosmetic applications when formulated to be non-irritating. While concentrations up to 49.5% were noted in hair relaxer formulations, this is not a general safe maximum for all cosmetic uses, especially skincare. It is classified as harmful if ingested and can cause skin and eye irritation, potentially leading to serious eye damage. It may also irritate the respiratory system. FDA has not explicitly stated its status for cosmetic use, though related carbonate salts are generally recognized as safe (GRAS) for food.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Valuable

Guanidine Carbonate is a valuable ingredient primarily for its robust pH adjusting and buffering capabilities, though its mild exfoliant and skin conditioning benefits require careful formulation to mitigate potential irritation risks.


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