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Moumoujus

GUAIACOL ACETATE.

Questionable CAS 613-70-7 / PERFUMING

Guaiacol Acetate, chemically known as 2-Methoxyphenyl acetate, is an aromatic compound widely recognized for its contributions as a flavoring agent and fragrance component. While approved for food use, its application in advanced skincare formulations lacks specific safety assessments and established dermatological benefits.

Summary

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

There is no available clinical research supporting specific skin benefits for Guaiacol Acetate in cosmetic applications, rendering any claims related to its efficacy in skincare unsubstantiated.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

This ingredient exhibits sensitivity to air and light, necessitating storage in tightly sealed containers under an inert gas, in a cool, dry, and well-ventilated environment, protected from heat and direct light.

Conflicts

  • strong oxidizing agents
  • strong bases

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

Although listed in the FDA Global Substance Registration System and possessing a FEMA number indicating approval as a flavoring agent in food, Guaiacol Acetate lacks specific FDA status or maximum concentration guidelines for cosmetic use. Neither the Cosmetic Ingredient Review (CIR) nor the Scientific Committee on Consumer Safety (SCCS) has conducted a dedicated safety assessment. Aggregated GHS data from the ECHA C&L Inventory indicates that it 'Causes skin irritation' (H315) in 22.4% of 116 reported instances.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

Guaiacol Acetate presents a moderate irritation risk and lacks scientific evidence for any skin benefits, making its inclusion in precision skincare formulations highly questionable without further robust research and safety assessments.

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