Science
Mechanism of Action
This ingredient functions by engaging with the sulfur bridges, specifically disulfide bonds, within the keratin structure of hair. This interaction facilitates chemical processes required for hair waving or straightening. No detailed mechanism of action or demonstrated efficacy for its direct application to skin for skincare benefits has been identified in the available research.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
As an ester, Glyceryl Thiopropionate is susceptible to hydrolysis, particularly under extreme pH conditions. While a pH of 6.5 was noted for propionic acid production via fermentation, this observation does not directly translate to optimal stability for this ingredient in cosmetic formulations.
Conflicts
- Strong oxidizing agents
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded in 2000 that Glyceryl Thiopropionate, within a class of glyceryl monoesters, is safe for use in cosmetics under current practices. A re-review is scheduled for 2025. Specific maximum concentrations for skin applications are not provided. For the structurally related Glyceryl Thioglycolate, it was deemed safe for hair products up to 15.2% (as Thioglycolic Acid), with recommendations for hairdressers to avoid skin contact and minimize consumer exposure due to potential irritation at higher concentrations or prolonged contact. Its irritancy for direct skin application remains unknown based on current data.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While generally considered safe for cosmetic use, there is currently insufficient data to establish specific skincare benefits or recommended application for Glyceryl Thiopropionate on skin.
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References
Sources