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Moumoujus

GLUTARIC ACID.

Avoid CAS 110-94-1 / BUFFERING

Glutaric Acid is a dicarboxylic acid primarily utilized in cosmetic formulations for its buffering properties, helping to maintain stable pH levels. Despite its role in formulation stability, caution is advised due to its high irritancy potential.

Summary

Buffering

Science

Mechanism of Action

It acts as a buffering agent, effectively stabilizing the pH of skincare formulations to ensure ingredient integrity and product efficacy.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This ingredient exhibits high solubility in water, dissolving significantly at 20 °C (e.g., over 50% w/w). It is also soluble in polar organic solvents like ethanol. Its pKa values are approximately 4.34 and 5.22, indicating that a pH below these values would favor its predominant acidic form in solution.

Conflicts

  • bases
  • oxidizing agents
  • strong reducing agents

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk High

The Cosmetic Ingredient Review (CIR) has evaluated Glutaric Acid, concluding with insufficient data for a comprehensive safety assessment. Safety profiles suggest a high risk of irritation, including severe skin burns and eye damage, and it is noted as irritating to the respiratory system and skin.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Due to its high irritancy potential, including the risk of severe skin burns, and insufficient safety data from CIR, Glutaric Acid is not recommended for use in precision skincare formulations.

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