Science
Mechanism of Action
This ingredient functions primarily as a fragrance component, delivering a lasting aroma to formulations. Beyond its aromatic contribution, geranyl isovalerate also exhibits skin-conditioning properties, helping to maintain skin health and texture.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The compound demonstrates robust stability under standard storage conditions, maintaining compatibility across a variety of cosmetic and food applications. It offers a shelf life of 36 months when stored in a tightly sealed container under inert gas in a cool, well-ventilated environment.
Safety
Safety Profile
Evaluations by RIFM indicate geranyl isovalerate is not genotoxic. However, based on human studies and read-across data, it is identified as a skin sensitizer, with a No-Expected Sensitization Induction Level (NESIL) of 5000 μg/cm2. Some reports also describe it as a skin irritant. Acute oral and dermal toxicity are low, with LD50 values exceeding 5 g/kg in rats and rabbits, respectively. Repeated dose toxicity showed a NOAEL of 1000 mg/kg/day, and developmental/fertility toxicity had a NOAEL of 440 mg/kg/day. While listed by the FDA as a GRAS flavoring agent (FEMA 2518), its use in skincare is restricted due to its sensitizing potential, though specific maximum concentrations for cosmetic use were not provided.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Geranyl isovalerate offers skin conditioning and a pleasant fragrance but its classification as a sensitizer and potential irritant makes it a questionable choice for precision skincare formulations, especially given the lack of specific efficacy data.
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References
Sources