Science
Mechanism of Action
This extract operates by scavenging free radicals, thereby protecting dermal cell membranes and the extracellular matrix from reactive oxygen species and UV radiation-induced damage. It also demonstrates hydrating capabilities through its ability to bind water molecules, which enhances the skin's moisture-retaining capacity, supporting volume, firmness, and elasticity. Preliminary in vitro data further suggests it can improve epidermal barrier function, mitigate inflammation, and potentially aid in acne management by inhibiting bacterial films via components like mannitol. Broader Fraxinus plant extracts indicate roles in regulating cellular proliferation and inflammation pathways, including increasing Bcl-2 expression and activating Nrf-2/ARE for enhanced antioxidant enzyme activity.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 In an in vitro ROS-scavenging activity test, Fraxinus ornus manna extract exhibited 23.71 ± 1.81% antioxidant activity.
Transparency
Dusting Analysis
Fraxinus Ornus Seed Extract is not commonly reported for cosmetic use under the FDA's Voluntary Cosmetics Reporting Program. This absence of reported use contributes to its 'insufficient data' status by the Cosmetic Ingredient Review (CIR), as there is limited widespread market presence or safety reporting.
The Formula
Formulation
Stability
A hydrogel complex containing Fraxinus ornus manna extract demonstrated suitable physicochemical properties and stability within a pH range of 5.50 to 6.80, suggesting that its water-soluble components are stable within this interval.
Safety
Safety Profile
Dermal, oral, and inhalation toxicity for Fraxinus Ornus Seed Extract have not been determined. Its 'insufficient data' CIR status is primarily due to a lack of reported uses within the FDA's Voluntary Cosmetics Reporting Program, rather than specific safety concerns or identified risks.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Fraxinus Ornus Seed Extract demonstrates promising antioxidant, hydrating, and barrier-supporting potential based on preliminary in vitro data, but its overall safety and efficacy warrant further comprehensive clinical investigation due to insufficient reported data.
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