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FRAXINUS ORNUS SEED EXTRACT.

Insufficient Data CAS 84929-21-5 / SKIN CONDITIONING

Fraxinus Ornus Seed Extract is a botanical ingredient recognized for its potent antioxidant and hydrating properties. It functions to protect dermal structures from environmental stressors and enhance skin's moisture retention, contributing to overall skin health and resilience.

Antioxidant Hydrating Skin Conditioning Barrier Support Anti-inflammatory Acne Treatment Support Anti-aging Support

Science

This extract operates by scavenging free radicals, thereby protecting dermal cell membranes and the extracellular matrix from reactive oxygen species and UV radiation-induced damage. It also demonstrates hydrating capabilities through its ability to bind water molecules, which enhances the skin's moisture-retaining capacity, supporting volume, firmness, and elasticity. Preliminary in vitro data further suggests it can improve epidermal barrier function, mitigate inflammation, and potentially aid in acne management by inhibiting bacterial films via components like mannitol. Broader Fraxinus plant extracts indicate roles in regulating cellular proliferation and inflammation pathways, including increasing Bcl-2 expression and activating Nrf-2/ARE for enhanced antioxidant enzyme activity.


Research

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In an in vitro ROS-scavenging activity test, Fraxinus ornus manna extract exhibited 23.71 ± 1.81% antioxidant activity.

Transparency

Not commonly dusted

Fraxinus Ornus Seed Extract is not commonly reported for cosmetic use under the FDA's Voluntary Cosmetics Reporting Program. This absence of reported use contributes to its 'insufficient data' status by the Cosmetic Ingredient Review (CIR), as there is limited widespread market presence or safety reporting.


The Formula

Solubility
Both
Optimal pH 5.5 – 6.8
0 7 14

Stability

A hydrogel complex containing Fraxinus ornus manna extract demonstrated suitable physicochemical properties and stability within a pH range of 5.50 to 6.80, suggesting that its water-soluble components are stable within this interval.


Safety

CIR Status
Insufficient data
Sensitization risk Unknown

Dermal, oral, and inhalation toxicity for Fraxinus Ornus Seed Extract have not been determined. Its 'insufficient data' CIR status is primarily due to a lack of reported uses within the FDA's Voluntary Cosmetics Reporting Program, rather than specific safety concerns or identified risks.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

Fraxinus Ornus Seed Extract demonstrates promising antioxidant, hydrating, and barrier-supporting potential based on preliminary in vitro data, but its overall safety and efficacy warrant further comprehensive clinical investigation due to insufficient reported data.


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