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Moumoujus

FORMAMIDINE SULFINIC ACID.

Avoid CAS 1758-73-2 / REDUCING

Formamidine Sulfinic Acid (FSA) is a potent reducing agent and zwitterionic antioxidant, fundamentally designed to alter chemical structures through the addition of hydrogen or removal of oxygen. While demonstrating significant therapeutic potential in a specific medical context at 5% concentration, its classification as hazardous severely restricts its suitability for general cosmetic applications.

Summary

Reducing Agent Antioxidant

Science

Mechanism of Action

Functioning as a strong reducing agent, Formamidine Sulfinic Acid undergoes an irreversible conversion to formamidine sulfonic acid within a formulation. It also exhibits properties as a zwitterionic antioxidant, facilitating chemical modifications by either donating hydrogen atoms or accepting oxygen atoms.

Research

Clinical Evidence

Insufficient-data confidence
Effective range 5–5%
Optimal

5%

Transparency

Dusting Analysis

Not commonly dusted

No data available to suggest common dusting or associated thresholds.

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 5
0 7 14

Stability

Formamidine Sulfinic Acid salts exhibit rapid decomposition in aqueous solutions, particularly exacerbated by alkaline conditions and elevated temperatures. Its saturated aqueous solution maintains a pH of 5.0. It possesses low thermal stability, characterized by a self-accelerating decomposition temperature (SADT) of 50°C. Optimal storage conditions recommend temperatures below 30°C in a dry, well-ventilated environment, shielded from moisture, heat, and direct sunlight.

Conflicts

  • Bases (alkaline conditions)
  • Strong oxidizing agents
  • Strong acids
  • Heat
  • Moisture
  • Combustible materials

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

Formamidine Sulfinic Acid is classified as hazardous, explicitly causing skin irritation and serious eye damage. It presents a risk of respiratory irritation and may be harmful if ingested or inhaled. Furthermore, it carries a potential for organ damage through prolonged or repeated exposure. Its inclusion is strictly advised against in food, drug, pesticide, or biocidal products.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Given its classification as hazardous, direct causation of skin and serious eye irritation, and potential for organ damage from exposure, Formamidine Sulfinic Acid is unequivocally unsuitable and advised against for any cosmetic skincare formulation.

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