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FORMALDEHYDE CYCLODECYL METHYL ACETAL.

Questionable CAS 42604-12-6 / PERFUMING

FORMALDEHYDE CYCLODECYL METHYL ACETAL is a fragrance compound. It is crucial to note that specific research data for this 'methyl' variant is currently unavailable; therefore, this profile is based entirely on the closely related compound, FORMALDEHYDE CYCLODECYL ETHYL ACETAL. It primarily functions to impart a diffuse woody scent with ambergris notes to cosmetic formulations.

fragrance perfuming

Science

This ingredient acts solely as a perfuming agent, designed to enhance the sensory experience of a product by delivering its characteristic woody, ambergris-like fragrance. There is no known direct mechanism of action that confers therapeutic or specific cosmetic benefits to the skin beyond its aromatic contribution.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

This analysis is not applicable as the ingredient functions purely as a fragrance.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Based on FORMALDEHYDE CYCLODECYL ETHYL ACETAL, this compound exhibits an estimated half-life at 25°C of 299 hours at pH 4, decreasing to 259 hours at pH 7, and 243 hours at pH 9, indicating reduced stability as pH increases. Strong acidic conditions are known to cleave the molecule.

Conflicts

  • strong acids

Safety

CIR Status
Safe with restrictions
Max tested
Maximum acceptable concentration levels are established by IFRA Standards and vary by specific product category.%
Sensitization risk Moderate

The safety of FORMALDEHYDE CYCLODECYL ETHYL ACETAL has been assessed by RIFM and deemed 'safe with restrictions,' with IFRA Standards governing its use to minimize risk. While it does not present a concern for genotoxicity, GHS classification data indicates a high propensity for skin irritation (>99.9% of reports) and eye irritation (11.2%). It has the potential for skin sensitization in a small fraction of individuals, with 86.5% of reports indicating it may cause an allergic skin reaction. Repeated dose toxicity studies show a No Observed Adverse Effect Level (NOAEL) of 333 mg/kg/day, and reproductive toxicity an NOAEL of 1000 mg/kg/day. The No Expected Sensitization Induction Level (NESIL) is 3500 μg/cm2.


Your Skin

No Normal
No Dry
Yes Oily
No Sensitive
Irritancy Medium
Comedogenicity Low

Our Assessment

Questionable

Primarily a fragrance ingredient, FORMALDEHYDE CYCLODECYL ETHYL ACETAL (on which this data is based) offers no direct skin benefits and carries a moderate risk of skin irritation and sensitization, making its inclusion in precision skincare formulations questionable.


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