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Moumoujus

FISH VITREOUS HUMOR EXTRACT.

Insufficient Data / HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Derived from the eye's clear gel, Fish Vitreous Humor Extract is a natural source of hyaluronic acid. Research suggests it offers hydrating, antioxidant, and anti-inflammatory benefits to the skin, while also promoting cell proliferation crucial for tissue regeneration.

Summary

Hydrating Antioxidant Anti-inflammatory Cell Proliferant Skin Conditioning

Science

Mechanism of Action

This extract functions primarily through its rich hyaluronic acid (HA) content, a highly hydrophilic molecule essential for maintaining tissue hydration and elasticity. Additionally, specific extracts from tuna vitreous humor have demonstrated antioxidant capabilities, helping to neutralize free radicals and combat oxidative stress. Its anti-inflammatory properties can soothe the skin, and its capacity to stimulate fibroblast cell proliferation supports skin repair and regeneration.

Research

Clinical Evidence

Low confidence
Effective range 0.05–0.075%
Optimal

N/A

Key findings

  1. 01 Tuna vitreous humor extracts, comprising both soluble and hyaluronic acid-rich precipitated fractions, exhibited antioxidant and anti-inflammatory effects. These extracts did not induce inflammation in human corneal epithelial cells, confirming safety in ophthalmic contexts. High cell viability (90%+) was maintained at concentrations up to 0.075% (0.75 mg/mL) for the soluble fraction and 0.05% (0.5 mg/mL) for the precipitated fraction.
  2. 02 Hyaluronic acid isolated from Nile tilapia vitreous humor was found to be non-cytotoxic and capable of stimulating fibroblast cell proliferation in vitro, suggesting potential for tissue repair and regeneration.

Transparency

Dusting Analysis

Not commonly dusted

While hyaluronic acid, a key component, is widely used, Fish Vitreous Humor Extract itself is not a commonly documented or widespread ingredient in cosmetic skincare products, hence not subject to typical dusting practices.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific safety assessments by CIR or SCCS for the full extract were identified. In vitro studies on purified hyaluronic acid from fish vitreous humor have indicated non-cytotoxicity, suggesting a favorable safety profile for these isolated components in ophthalmic applications. However, comprehensive safety data for the intact extract in topical skincare is limited.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While offering promising hydration, antioxidant, and regenerative benefits through its hyaluronic acid content, current research primarily supports ophthalmic and biomedical applications, indicating insufficient specific data for widespread direct use in skincare.

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References

Sources