Science
Mechanism of Action
Primarily functioning as a skin conditioning agent, Ficus Erecta Branch/Leaf Extract has demonstrated anti-inflammatory and antioxidative capabilities in studies involving its ethanol extract, particularly in traditional medicine contexts. While its precise topical mechanism for cosmetic applications requires further elucidation, observed effects include anti-neuroinflammatory activity in microglia, evidenced by the inhibition of nitrate and prostaglandin E2 production.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Information regarding optimal pH and solubility is not specified. However, the extract may present aesthetic, stability, or other formulation challenges that could restrict its utility in cosmetic preparations.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not evaluated Ficus Erecta Branch/Leaf Extract. While topical safety data is limited, oral toxicity studies in rats using the ethanol extract revealed no adverse effects or mortality up to 5000 mg/kg in acute tests, and a No Observed Adverse Effect Level (NOAEL) of 2000 mg/kg/day over 13 weeks. Genotoxicity tests also indicated no significant genotoxic effects at concentrations up to 312.5 µg/plate and 31.3 µg/mL.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Further specific topical efficacy and formulation stability data are required to ascertain the full cosmetic utility of Ficus Erecta Branch/Leaf Extract.
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