Science
Mechanism of Action
This ingredient, part of the Tosylamide/Epoxy Resin class, operates by creating a continuous, durable, and flexible film. In nail applications, this film enhances gloss, strengthens the nail surface, improves adhesion of varnishes, and prevents wear. Its direct mechanism for beneficial effects on skin, beyond forming a film, has not been identified or described in available research.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
This ingredient is a resin primarily utilized in nail products and is not typically 'dusted' in skincare formulations for any recognized therapeutic effect.
The Formula
Formulation
Stability
Hydrolysis is not anticipated within the typical environmental pH range of 4.0-9.0 due to its low solubility. For optimal stability, storage in original, tightly-sealed packaging, in a dry, well-ventilated environment away from direct sunlight and below 25 °C, is recommended.
Conflicts
- amines (curing agents)
- amides (curing agents)
- solvents reactive with epoxy groups (e.g., ethanol, isopropanol)
Safety
Safety Profile
Despite very low irritation observed in rabbit skin tests, ETHYLTOSYLAMIDE EPOXY RESIN-2 is a known and well-documented cause of allergic contact dermatitis in humans, frequently appearing on areas like the neck, face, and eyelids from contact with nail products. Its component, Ethyl Tosylamide (CAS 80-39-7), is banned for cosmetic use in Europe due to its potential for allergic reactions and classification as a major hormonal disrupter. The EWG designates Tosylamide/Epoxy Resin as 'Unacceptable' for EWG VERIFIED products due to allergy and immunotoxicity concerns. The CIR Expert Panel found insufficient data for this specific polymer, although an analogous polymer, Tosylamide Formaldehyde resin, was deemed safe in nail products up to 10%.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While ETHYLTOSYLAMIDE EPOXY RESIN-2 is a common film-former in nail products, its high potential for allergic contact dermatitis and regulatory concerns regarding its components make it unsuitable for precision skincare formulations.
Related
Similar Ingredients
Finding similar ingredients…