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ETHYLBENZENE.

Avoid CAS 100-41-4 / PERFUMING

Ethylbenzene is an aromatic hydrocarbon recognized primarily for its industrial solvent properties rather than any beneficial dermatological actions. It is readily absorbed through human skin and is associated with significant irritant and toxicological concerns, making it unsuitable for skincare formulations.

Science

Ethylbenzene does not possess any beneficial mechanism of action on the skin. Its interaction is characterized by solvent effects that can compromise the skin barrier and induce irritation. Once absorbed transdermally, it is metabolized internally, contributing to its systemic toxicological profile.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Ethylbenzene is not an active ingredient in cosmetic science; it functions as an industrial solvent and potential impurity, offering no recognized benefits for skin health or appearance.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Conflicts

  • Strong oxidizing materials (reacts vigorously)
  • Not supported for use as a solvent in consumer products

Safety

CIR Status
Not reviewed
Sensitization risk High

The International Agency for Research on Cancer (IARC) classifies ethylbenzene as possibly carcinogenic to humans (category 2B), though regulatory bodies in the US and EU do not classify it as a carcinogen. The US EPA suspended its assessment in 2019. It is a documented skin and serious eye irritant. Prolonged dermal exposure can lead to drying, scaling, and blistering of the skin. Its application as a solvent in consumer or professional sectors is not recommended, and its presence in cosmetic formulations is generally considered an impurity due to its hazardous characteristics.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Ethylbenzene is a hazardous industrial chemical with no beneficial skin properties, presenting high irritancy and potential carcinogenic concerns, and should be unequivocally avoided in skincare formulations.


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