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ETHYL VANILLIN.

Questionable CAS 121-32-4 / FRAGRANCE, SOOTHING

Ethyl Vanillin is a synthetic aromatic compound primarily employed for its sweet, vanilla-like fragrance and flavor-masking properties in skincare. It also exhibits antioxidant capabilities and can offer a soothing sensation to mildly irritated skin.

fragrance masking antioxidant soothing

Science

Ethyl Vanillin operates as an antioxidant, helping to neutralize free radicals and mitigate oxidative stress on the skin. Its presence as a fragrance agent contributes to the product's sensory profile, while also demonstrating a capacity to calm minor skin irritations.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH 1 – 7
0 7 14

Stability

Ethyl Vanillin is sensitive to environmental factors; it can develop a red coloration and diminish in fragrance potency upon exposure to iron or alkaline conditions. It is also susceptible to degradation by light and is hygroscopic, meaning it readily absorbs moisture from the air.

Conflicts

  • iron
  • alkali
  • light

Safety

CIR Status
Not reviewed
Sensitization risk High

The Cosmetic Ingredient Review (CIR) Expert Panel has not conducted a dedicated safety assessment for Ethyl Vanillin in cosmetics, though it is used as a read-across analog for other fragrance ingredients. In contrast, the European Commission's Scientific Committee on Consumer Safety (SCCS) has reported evidence of its potential to cause contact allergy in humans. While the U.S. FDA deems it Generally Recognized as Safe (GRAS) for food additive use, this status does not directly translate to topical skincare safety.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Questionable

Despite its antioxidant and soothing potential, Ethyl Vanillin carries a significant risk of contact allergy according to SCCS, making its inclusion in precision skincare questionable, particularly for sensitive individuals, even though raw data suggests compatibility with sensitive skin.


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