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Moumoujus

ETHYL VANILLATE.

Questionable CAS 617-05-0 / PERFUMING

Ethyl Vanillate is a synthetic derivative primarily recognized for its potent antioxidant properties, particularly its ability to scavenge hydrogen peroxide. While demonstrating targeted efficacy as an adjunct therapy for specific dermatological conditions like vitiligo, its broader application in precision skincare warrants careful consideration due to noted irritation risks and limited general efficacy data.

Summary

Antioxidant Hydrogen peroxide scavenger Repigmenting agent (adjunct) Fragrance ingredient

Science

Mechanism of Action

This compound functions as a strong scavenger of hydrogen peroxide, a reactive oxygen species implicated in oxidative stress and cellular damage, such as melanocyte death in vitiligo. Additionally, it exhibits general antioxidant activity, helping to neutralize other toxic free radicals within the skin.

Research

Clinical Evidence

Medium confidence
Effective range 20–20%
Optimal

20%

Transparency

Dusting Analysis

Not commonly dusted

No data available to suggest common 'dusting' or concerns regarding specific percentages outside of clinical efficacy trials.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

For optimal stability, Ethyl Vanillate should be stored in a tightly-closed container in a cool, dry, and well-ventilated environment, kept away from incompatible substances and sources of ignition.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

Ethyl Vanillate has not been individually reviewed by the Cosmetic Ingredient Review (CIR) Expert Panel, although broader 'Vanilla-Derived Ingredients' have been assessed. No specific SCCS opinion is available. General GHS classifications indicate that approximately 29.7% of reports classify it as 'Harmful if swallowed,' 'Causes skin irritation,' 'Causes serious eye irritation,' and 'May cause respiratory irritation.' For the majority of reports (70.3%), it does not meet GHS hazard criteria. Some manufacturers label their Ethyl Vanillate products for 'research use only,' advising against personal consumption due to potential dangers or ineffectiveness.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

While demonstrating targeted efficacy in vitiligo management, the ingredient's general cosmetic utility is limited by specific safety considerations, including potential skin irritation, and a lack of broader clinical validation for widespread skincare benefits.

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