Science
Mechanism of Action
This compound acts as a transdermal absorption enhancer by influencing the multilamellar liposome structure of the stratum corneum lipids, thereby facilitating the penetration of other active substances through the skin barrier.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
N-Ethyl-2-pyrrolidone generally exhibits good chemical stability. A solution in water at 100g/L and 20°C presents a weakly alkaline pH ranging from 8 to 9.
Conflicts
- Alkali (lye)
- Strong acid
Safety
Safety Profile
N-Ethyl-2-pyrrolidone (NEP) is classified by ECHA as a reproductive toxicant, indicating potential harm to fertility or unborn children, and it is known to cause serious eye damage. It is explicitly listed in Annex II of the EU Cosmetic Products Regulation, making its use in cosmetics illegal within the European Union. Although the Cosmetic Ingredient Review (CIR) Expert Panel has not directly assessed 'ETHYL PYRROLIDONE' but has reviewed related vinylpyrrolidone polymers, its documented hazards raise substantial safety concerns for cosmetic formulations, despite not being explicitly banned by the FDA in the US.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Due to its classification as a reproductive toxicant, high irritancy profile, and explicit prohibition for cosmetic use in the European Union, Ethyl Pyrrolidone is strictly unsuitable for skincare formulations.
Related
Similar Ingredients
Finding similar ingredients…