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ETHYL PHENYLACETATE.

Valuable CAS 101-97-3 / PERFUMING

Ethyl Phenylacetate is a versatile ester primarily employed in skincare as a fragrance component and solvent. It imparts a subtle, long-lasting scent while contributing to the overall formulation texture.

fragrance solvent fixative

Science

Operating as both a solvent and a fragrance agent, Ethyl Phenylacetate enhances the texture and aromatic profile of personal care products. Its fixative properties are key, enabling a gradual, sustained release of fragrance, thereby extending the longevity of a product's scent.


Research

Medium confidence
Effective range 0.1–0.5%
Optimal

N/A

Key findings

  1. 01 Human maximization tests at 8% concentration demonstrated no skin sensitization reactions, indicating a low potential for allergic responses in cosmetic applications.
  2. 02 In skincare products like hand creams and moisturizers, it is typically used at concentrations between 0.1% and 0.5% for subtle, slow-release fragrance contribution.

Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH 4.5 – 6.5
0 7 14

Stability

A relatively stable ester, Ethyl Phenylacetate resists hydrolysis under normal storage conditions. Protection from strong acids or bases is crucial to prevent ester cleavage. While specific optimal pH is not explicitly stated, esters generally maintain stability within typical cosmetic pH ranges of 4.5-6.5.

Conflicts

  • strong acids
  • strong bases

Safety

CIR Status
Not reviewed
Max tested
3%
Sensitization risk Low

Recognized as Generally Recognized As Safe (GRAS) by FEMA (#2452) for food use and approved by the FDA as a direct food additive. Extensive human patch testing revealed no irritation at concentrations up to 8%. It exhibits low sensitization potential, is non-genotoxic, and is not expected to be phototoxic or photoallergenic.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

Ethyl Phenylacetate is a valuable ingredient for its ability to provide subtle, long-lasting fragrance and its excellent safety profile across all skin types.


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