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ETHYL METHOXYCINNAMATE.

Valuable CAS 99880-64-5 / UV ABSORBER

Ethyl Methoxycinnamate, commonly known as Octinoxate, is an organic chemical UV filter extensively used in skincare for its photoprotective properties. It specifically targets and absorbs harmful UVB radiation, contributing to the prevention of sunburn and premature skin aging.

sunscreen uv absorber uv filter

Science

This oil-soluble liquid operates by forming a protective layer on the skin that absorbs UVB radiation within the 280-320 nm wavelength range, with peak absorption at 310 nm. It converts the absorbed UV energy into less damaging heat, thus preventing epidermal damage. While highly effective against UVB, it does not provide UVA protection, necessitating its combination with other filters for broad-spectrum defense.


Research

High confidence
Effective range 1–10%
Optimal

7.5%

Key findings

  1. 01 Approved maximum concentration in the US for sunscreen formulations to provide robust UVB protection.
  2. 02 Approved maximum concentration in the EU across various cosmetic products, including sunscreens, demonstrating effective UVB protection and deemed safe for children.
  3. 03 Widely utilized as a primary UVB filter in concentrations ranging from 1% in lip balms to 7.5% in sunscreen creams and lotions, contributing significantly to SPF ratings.

Transparency

Not commonly dusted

Ethyl Methoxycinnamate is an active ingredient whose UV filtering efficacy is concentration-dependent within regulatory limits. Its function requires specific percentages to provide adequate sun protection, rendering it unsuitable for 'dusting' or sub-threshold usage for marketing purposes.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

As an oil-soluble liquid, Ethyl Methoxycinnamate can undergo photodegradation upon sun exposure, leading to a reduction in its SPF efficacy. To enhance stability and ensure sustained performance, it should be formulated with other UV filters (e.g., Tinosorb S, Octocrylene) and supplemented with antioxidants (e.g., Vitamin E, BHT) to prevent oxidative degradation.

Synergies

  • Other UVB filters (e.g., Tinosorb S, Octocrylene) for enhanced photostability and efficacy.
  • UVA filters for comprehensive broad-spectrum UV protection.
  • Antioxidants (e.g., Vitamin E, BHT) to mitigate oxidative instability.

Conflicts

  • Significant photodegradation when exposed to sunlight without stabilizing co-filters.
  • Lacks standalone UVA protection, requiring combination with UVA filters for broad-spectrum benefits.

Safety

CIR Status
Not reviewed
Max tested
10%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) defers its safety assessment to the FDA, which approves its use as an active ingredient in OTC sunscreen products up to 7.5% in the United States. The European Commission's SCCS confirms its safety up to 10% in various cosmetic products, including for children. However, the SCCS has identified it as an endocrine-active substance, exhibiting estrogenic and weak anti-androgenic activity in both in vitro and in vivo studies.


Your Skin

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Ethyl Methoxycinnamate is a valuable and well-established UVB filter crucial for effective sun protection, though precision formulations should consider its identified endocrine-active properties as noted by regulatory bodies.


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