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ETHYL HYDROXY PICOLINIUM LACTATE.

Insufficient Data CAS 220610-55-9 / SKIN CONDITIONING

Ethyl Hydroxy Picolinium Lactate is a novel salt formed by the precise union of 6-methyl-2-ethyl-3-hydroxypyridine (Emoxypine) and Lactic Acid. This sophisticated compound is designed to offer a multifaceted approach to skin health, combining potent antioxidant and anti-inflammatory properties with gentle exfoliation and hydration.

Antioxidant Anti-inflammatory Membrane-protective Exfoliant Hydrating Skin conditioning

Science

This ingredient functions via a dual mechanism, leveraging the distinct attributes of its constituent compounds. The Emoxypine component provides robust antioxidant defense by inhibiting free radical generation, upregulating endogenous antioxidant enzymes, and protecting biomembrane lipids from oxidative stress. It also exhibits anti-inflammatory effects by modulating inflammatory pathways. Concurrently, the Lactic Acid component, an Alpha Hydroxy Acid (AHA), facilitates mild epidermal exfoliation by accelerating cellular turnover and aiding in the removal of devitalized corneocytes, while simultaneously drawing and retaining moisture to enhance skin hydration.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

No specific information regarding 'dusting' or overhyped claims for this ingredient was found in the research data. Its status as a relatively less-known combined molecule suggests it is not currently subject to widespread 'dusting' practices.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While specific optimal pH and stability data for Ethyl Hydroxy Picolinium Lactate itself are not explicitly reported, its Lactic Acid component (Ethyl Lactate) is known to be susceptible to degradation through hydrolysis in the presence of water, acids, and bases. It is also prone to oxidation. Formulators should consider storing the ingredient under inert conditions and may benefit from incorporating antioxidants such as ascorbic acid or butylated hydroxytoluene (BHT) to enhance its overall stability.


Safety

CIR Status
Not reviewed
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically assessed Ethyl Hydroxy Picolinium Lactate. However, its Lactic Acid component has been reviewed, with conclusions of safety for cosmetic use at concentrations of 10% or less, in formulations with a final pH of 3.5 or greater, provided sun sensitivity is mitigated or daily sun protection is directed. For salon products, concentrations up to 30% are deemed safe at a pH of 3.0 or greater for brief, discontinuous professional use, also requiring sun protection. The ingredient is listed in the FDA Global Substance Registration System (GSRS) under UNII 84438Y4KT6. No specific SCCS (Scientific Committee on Consumer Safety) opinion for this ingredient was identified.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Insufficient Data

While offering a theoretically promising combination of antioxidant, anti-inflammatory, exfoliating, and hydrating properties derived from its well-understood components, robust clinical data specifically validating the efficacy and optimal usage of Ethyl Hydroxy Picolinium Lactate as a singular combined ingredient is currently insufficient for a definitive rating.


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