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ETHYL CYANOACRYLATE.

Avoid CAS 7085-85-0 / FILM FORMING

Ethyl cyanoacrylate is a highly reactive monomer known for its potent and rapid adhesive properties. It forms a strong, durable film upon polymerization, primarily bonding to keratinous surfaces like skin. While crucial in various adhesive applications, its significant irritant and sensitizing profile renders it largely unsuitable for direct, routine use in precision skincare.

Film Forming Adhesive

Science

This compound undergoes rapid anionic polymerization when exposed to minute amounts of moisture, such as atmospheric humidity, or weak basic compounds. Moisture initiates the reaction by acting as a nucleophile, attacking the electrophilic carbon-carbon double bond within the cyanoacrylate molecule. This action leads to bond rupture and the formation of a highly reactive anion, which then propagates a chain reaction. The outcome is the formation of long polymer chains that establish a robust adhesive bond, notably to surface keratin on the skin.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Ethyl cyanoacrylate is a liquid monomer engineered for rapid polymerization into a solid adhesive film rather than being utilized as a powder or 'dusted' ingredient in cosmetic formulations. Its functional role involves curing on contact to form a strong bond, not offering typical skincare benefits via dusting.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Formulations containing ethyl cyanoacrylate must be maintained in an anhydrous state and protected from basic compounds, as the ingredient polymerizes rapidly upon contact with moisture or weak bases, initiating the curing process. Lower temperatures can retard the drying process, whereas higher temperatures accelerate it. Meticulous moisture management is paramount for ensuring consistent and reliable product performance.

Conflicts

  • Water / Moisture
  • Weakly basic compounds
  • Amines
  • Sulfur compounds
  • Certain metals (e.g., copper, brass)

Safety

CIR Status
Not reviewed
Max tested
90%
Sensitization risk High

Ethyl cyanoacrylate is classified as a strong irritant to the lungs, eyes, and skin. It is a known sensitizer, with frequent exposure in cosmetic applications like nail or eyelash glues potentially leading to allergic contact dermatitis. During degradation, polymerized cyanoacrylates may release formaldehyde, itself a potent sensitizer. The FDA has noted common reported responses to cyanoacrylate tissue adhesives, including inflammation, bleeding, discharge, erythema, keloid formation, and allergic reactions. Canada has restricted the use of cyanoacrylate-based eyelash glues to professional settings due to these safety concerns. The stated maximum concentration of 90% refers to its use in specific adhesive products like eyelash glues, where its application is associated with these inherent risks.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Due to its severe irritancy, high sensitization potential, and primary function as an adhesive rather than a beneficial skincare ingredient, ethyl cyanoacrylate should be avoided in precision topical skincare formulations.


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