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Moumoujus

ETHYL ACETATE.

Valuable CAS 141-78-6 / PERFUMING, SOLVENT

Ethyl Acetate is a versatile organic compound primarily functioning as a solvent and diluent in precision skincare formulations. Valued for its rapid evaporation, it aids in dissolving other ingredients and enhancing the spreadability of products without leaving residue.

Summary

perfuming solvent diluent penetration enhancer antimicrobial

Science

Mechanism of Action

As a solvent, Ethyl Acetate efficiently dissolves various cosmetic components, including film-forming agents, and acts as a perfume carrier, allowing fragrances to dissipate effectively. It can also function as a penetration enhancer, potentially improving the absorption of other active ingredients into the skin, while also exhibiting antimicrobial properties.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Demonstrated efficacy as an antimicrobial agent at a 5% concentration.
  2. 02 An ethyl acetate extract of Oryza sativa Indica (rice) was effective in inhibiting melanin production in human skin trials, indicating its utility as an extraction solvent for skin-brightening compounds.
  3. 03 An ethyl acetate fraction of Padina boergesenii brown seaweed showed potential in sunscreen creams to inhibit cell damage from UVB irradiation, highlighting its role in extracting photo-protective compounds.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Ethyl acetate slowly degrades in the presence of moisture. Its high volatility necessitates careful packaging and formulation to maintain product consistency and active ingredient efficacy over time.

Conflicts

  • strong bases
  • strong acids
  • ignition sources
  • oxidizing materials
  • lithium tetrahydroaluminate
  • potassium tert-butoxide
  • chlorosulfonic acid
  • (LiAlH2 + 2-chloromethyl furan)
  • oleum

Safety

Safety Profile

CIR Status
Safe with restrictions
Sensitization risk Moderate

The CIR Expert Panel deems Ethyl Acetate safe when formulated to be non-irritating. The EU requires its listing above 0.001% in leave-on and 0.01% in rinse-off products. While the FDA recognizes it as GRAS for food, high concentrations in skincare can induce skin dryness, irritation, or allergic reactions, particularly for sensitive skin types.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Ethyl Acetate is a valuable formulating agent for its solvent and carrier capabilities, requiring precise concentration control to mitigate potential irritation for sensitive and dry skin.

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