Science
Mechanism of Action
This compound functions primarily as a fragrance component, contributing aromatic properties to formulations. No specific mechanism of action on the skin for direct skincare benefits has been identified in existing research.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The compound generally exhibits stability under typical conditions and within perfumes and various functional bases. However, it demonstrates poor stability in the presence of strong oxidizers like liquid bleach, highly acidic cleaner liquids, aftershave formulations, cold wave lotions, and very alkaline products.
Conflicts
- liquid bleach
- acidic cleaner liquid
- aftershave
- cold wave lotion
- very alkaline products
Safety
Safety Profile
Ethyl 2,6,6-trimethylcyclohexa-2,4-dienecarboxylate, also known as Ethyl Safranate (CAS 35044-57-6), has undergone safety assessments by RIFM for its use as a fragrance ingredient. Human Repeated Insult Patch Test (HRIPT) studies have confirmed a lack of skin sensitization at defined doses. While an SDS indicates it 'Causes mild skin irritation,' it does not meet GHS hazard criteria. EWG Skin Deep rates it 'LOW' across categories including Cancer, Allergies & Immunotoxicity, and Developmental and Reproductive Toxicity. Environment Canada classifies it as 'not expected to be potentially toxic or harmful,' 'not suspected to be persistent,' 'not suspected to be bioaccumulative,' and 'not suspected to be an environmental toxin.' The ingredient is typically limited to 5% in fragrance concentrates.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Primarily a fragrance ingredient, this compound lacks identified direct skincare benefits, thus warranting an 'insufficient-data' verdict for efficacy, despite its established safety profile as a perfuming agent.
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References
Sources