Science
Mechanism of Action
This ingredient functions effectively as a pH adjuster and buffering agent, contributing to formulation stability and texture. While Ethanolamine HCl directly supports product integrity, studies on its analog, N-(2-Aminoethyl) Ethanolamine (AEEA), indicate it can interact with the 3D structure of type I collagen, thereby increasing its extractability in human primary dermal fibroblasts and hinting at potential connective tissue modulation.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Ethanolamine HCl is stable but hygroscopic, necessitating storage below +30°C and protection from moisture. Its pKa is 9.5 at 25°C, providing robust buffering capacity, with solution pH typically reported between 9 and 10.
Conflicts
- Bases
- Strong oxidizing agents
Safety
Safety Profile
The CIR Expert Panel deems Ethanolamine and its salts, including Ethanolamine HCl, safe for use in present practices and concentrations, specifically in rinse-off products, provided the final formulation is non-irritating. It is crucial to avoid its use in cosmetic products where the formation of N-nitroso compounds is possible. While no specific maximum concentration for Ethanolamine HCl is universally established, its parent compound, Ethanolamine, has been reported in rinse-off products at concentrations up to 18%. The high irritancy potential requires rigorous formulation testing.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Ethanolamine HCl is a valuable formulation aid as a pH adjuster, yet its classification as a high irritant means it demands stringent formulation to ensure product safety and minimize skin adverse reactions, limiting its direct skin benefit applications.
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References
Sources