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Moumoujus

ERIOBOTRYA JAPONICA SEED EXTRACT.

Insufficient Data CAS 91770-19-3 / BLEACHING, SKIN CONDITIONING

Eriobotrya Japonica Seed Extract, derived from the loquat tree, is a multi-functional botanical ingredient recognized for its antioxidant, anti-inflammatory, and anti-aging properties. It offers cellular protection and supports skin health by addressing oxidative stress and enzymatic degradation.

Summary

Antioxidant Anti-inflammatory Anti-aging Immunomodulatory Antimicrobial

Science

Mechanism of Action

This extract operates through multiple pathways: its rich phenolic and flavonoid content provides robust antioxidant defense by scavenging free radicals. It demonstrates anti-inflammatory action by calming inflammatory responses and potentially inhibiting pro-inflammatory mediators. Furthermore, it exhibits anti-aging effects by impeding the activity of collagenase and hyaluronidase, enzymes responsible for degrading crucial structural components like collagen and hyaluronic acid, thus contributing to improved skin softness and suppleness. Preliminary data also suggest antimicrobial activity.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro studies on cultured rat fibroblasts indicate anti-aging capabilities, demonstrating cellular aging amelioration and restoration of bradykinin-induced Ca2+ dynamics in senescent cells to youthful levels after seven days of treatment.
  2. 02 Rat models showed an immunomodulatory effect on allergic dermatitis, suggesting potential for soothing irritated skin.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) has not yet evaluated Eriobotrya Japonica Seed Extract. While an ethanol extract of Eriobotrya japonica leaves was deemed non-irritant for skin and eye in animal alternative tests, a specific safety assessment for the seed extract by CIR, SCCS, or FDA is not available, thus precise irritation and sensitization potential for this specific extract remains to be fully established.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Eriobotrya Japonica Seed Extract shows promising multi-functional benefits in preliminary in vitro and animal studies, particularly for anti-aging and anti-inflammatory action, but further human clinical trials and comprehensive safety assessments are required for full substantiation.

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