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EPOXYCYCLOHEXYLETHYL POLYSILSESQUIOXANE.

Valuable CAS 187333-74-0 / NAIL CONDITIONING

Epoxycyclohexylethyl Polysilsesquioxane is a sophisticated hybrid polymer, featuring an inorganic silsesquioxane core augmented with organic epoxycyclohexyl ethyl groups. It primarily forms a flexible, water-resistant film on the skin, enhancing product longevity and providing environmental resilience.

Summary

Film Former UV Absorber Compatibilizer Rheological Diluent Dispersant Emollient Viscosity Modifier

Science

Mechanism of Action

This hybrid molecule operates by creating a durable, water-resistant film on the skin's surface, offering robust protection against environmental degradation, moisture loss, and oxidation. It also effectively absorbs UV C and B radiation. Beyond its film-forming capabilities, it functions as a compatibilizer, rheological diluent, and dispersant, facilitating uniform distribution of other ingredients, and is also recognized for its emollient and viscosity-modifying properties.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This ingredient provides inherent chemical and thermal stability to coatings. Polysilsesquioxane resins containing silanols can undergo curing at elevated temperatures to form resilient binders or films, though formulation and catalysis are typically performed at or below room temperature to control this process.

Conflicts

  • Cationic photo-initiators (if curing is not desired)
  • Aromatic and aliphatic amines (if curing is not desired)
  • Catalysts such as dibutyltindiacetate, zinc acetate, or zinc 2-ethylhexanoate (if curing is not desired)
  • Nucleophiles (due to reactive epoxycyclohexyl group)
  • Protic surfaces (due to reactive epoxycyclohexyl group)

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed Epoxycyclohexylethyl Polysilsesquioxane, along with 17 other polysilsesquioxane derivatives, safe for cosmetic applications at current usage concentrations. Its substantial molecular volume significantly reduces the likelihood of notable dermal penetration. General studies indicate polysilsesquioxanes are non-irritating to rabbits at 100% concentration, with only minor localized effects (slight erythema and dryness) observed in specific instances at high concentrations for related compounds.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Epoxycyclohexylethyl Polysilsesquioxane is a valuable ingredient for enhancing product durability, providing environmental protection including UV absorption, and improving formulation aesthetics through its film-forming, stabilizing, and texture-modifying properties.

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