Science
Mechanism of Action
The Saururus Chinensis Extract Ferment Filtrate component is recognized for its antioxidant, brightening, soothing, and antimicrobial characteristics, attributed to active compounds such as Quercetin and Methyl-n-nonyl-ketone, which also contribute to detoxification. Concurrently, the Enterococcus Faecium ferment component actively promotes the self-renewal and proliferation of skin-derived precursor cells (SKPs). This is evidenced by an increase in the size of cellular spheres, an elevated proliferation rate, and a greater proportion of cells entering the S-phase of the cell cycle, driven by the activation of the PI3K/Akt signaling pathway. These actions collectively suggest potential regenerative and anti-aging effects on the skin.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Enterococcus faecium strains demonstrate notable stability in acidic environments, with approximately 76-78% survival observed at pH 3.0-4.0 and about 20-25% survival at pH 1.0-2.0. Additionally, some bacteriocins derived from Enterococcus faecium exhibit stability across a broad pH range and at elevated temperatures. Optimal pH for the growth and bacteriocin production of certain Enterococcus faecium strains can be around pH 8.0, with fermentation processes often maintained above pH 6.0 or adjusted to pH 6.4. However, the precise optimal pH range for the stability of the combined ferment filtrate itself has not been explicitly determined.
Safety
Safety Profile
The specific ingredient, ENTEROCOCCUS FAECIUM/SAURURUS CHINENSIS EXTRACT FERMENT FILTRATE, has not undergone individual safety assessment by leading regulatory bodies such as CIR, SCCS, or FDA for cosmetic application. While general safety evaluations exist for broader categories like yeast-derived or lactobacillus ferments, and for specific Enterococcus faecium strains used in food or probiotic contexts, a direct assessment for this unique combination in cosmetics is absent. It is crucial to distinguish between clinical isolates of Enterococcus faecium, which may carry virulence factors and antibiotic resistance, and strains isolated from fermented foods, which typically exhibit low antibiotic resistance and minimal intrinsic virulence traits.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This ingredient presents intriguing potential for skin regeneration, anti-aging, and multi-beneficial properties through its dual ferment components; however, comprehensive clinical data and specific safety reviews for this combined ingredient are currently unavailable.
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