Science
Mechanism of Action
This ferment operates through several key mechanisms. It produces antibacterial peptides, specifically CBT-SL5, which demonstrate efficacy against *Cutibacterium acnes*, a primary contributor to acne vulgaris. Beyond its direct antimicrobial action, it exhibits anti-inflammatory effects and contributes to the regulation of skin pH. As a postbiotic, it supports the maintenance of a healthy skin microbiome, leading to stabilization of skin health, reduction in redness, and potential improvements in skin elasticity and anti-aging benefits, all without causing irritation.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 A clinical study indicated that a lotion containing *Enterococcus faecalis* SL-5 significantly reduced pustules compared to a placebo, suggesting its potential as an alternative to topical antibiotics for acne management.
- 02 In a randomized controlled trial involving 20 Korean adults with mild to moderate acne, a facial lotion enriched with *Enterococcus faecalis* CBT SL-5 fermentation extract, applied twice daily for 4 weeks, led to significantly greater improvement in facial acne versus a control lotion.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The ferment products are generally reported to exhibit good stability, high-temperature resistance, and resilience across a wide pH range, from acidic to alkaline conditions. Precise optimal pH values for cosmetic formulation stability are not detailed.
Safety
Safety Profile
While the European Food Safety Authority (EFSA) and the Qualified Presumption of Safety (QPS) list do not include the genus *Enterococcus* due to concerns regarding live bacteria potentially acquiring virulence or antibiotic resistance, these concerns generally pertain to live bacterial applications in food or medicine. For inactivated cosmetic ingredients like this ferment, such risks are not directly applicable. However, specific cosmetic safety assessments by CIR, SCCS, or FDA, including maximum usage concentrations, are currently unavailable in the provided data.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Enterococcus Faecalis Ferment is a valuable postbiotic ingredient, demonstrating clinical efficacy in reducing acne and supporting a balanced skin microbiome with a low risk of irritation, making it highly suitable for targeted skincare formulations.
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References
Sources