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ENTEROCOCCUS FAECALIS FERMENT.

Valuable / ANTIMICROBIAL, SKIN PROTECTING

Enterococcus Faecalis Ferment is a postbiotic ingredient derived from the fermentation of the bacterium *Enterococcus faecalis*. It functions as a multifaceted skin conditioner, offering significant benefits for acne-prone skin, supported by its antimicrobial, anti-inflammatory, and microbiome-balancing properties.

skin conditioning anti-acne moisturizing humectant antimicrobial anti-inflammatory microbiome support

Science

This ferment operates through several key mechanisms. It produces antibacterial peptides, specifically CBT-SL5, which demonstrate efficacy against *Cutibacterium acnes*, a primary contributor to acne vulgaris. Beyond its direct antimicrobial action, it exhibits anti-inflammatory effects and contributes to the regulation of skin pH. As a postbiotic, it supports the maintenance of a healthy skin microbiome, leading to stabilization of skin health, reduction in redness, and potential improvements in skin elasticity and anti-aging benefits, all without causing irritation.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 A clinical study indicated that a lotion containing *Enterococcus faecalis* SL-5 significantly reduced pustules compared to a placebo, suggesting its potential as an alternative to topical antibiotics for acne management.
  2. 02 In a randomized controlled trial involving 20 Korean adults with mild to moderate acne, a facial lotion enriched with *Enterococcus faecalis* CBT SL-5 fermentation extract, applied twice daily for 4 weeks, led to significantly greater improvement in facial acne versus a control lotion.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The ferment products are generally reported to exhibit good stability, high-temperature resistance, and resilience across a wide pH range, from acidic to alkaline conditions. Precise optimal pH values for cosmetic formulation stability are not detailed.


Safety

CIR Status
Insufficient data
Sensitization risk Low

While the European Food Safety Authority (EFSA) and the Qualified Presumption of Safety (QPS) list do not include the genus *Enterococcus* due to concerns regarding live bacteria potentially acquiring virulence or antibiotic resistance, these concerns generally pertain to live bacterial applications in food or medicine. For inactivated cosmetic ingredients like this ferment, such risks are not directly applicable. However, specific cosmetic safety assessments by CIR, SCCS, or FDA, including maximum usage concentrations, are currently unavailable in the provided data.


Your Skin

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Enterococcus Faecalis Ferment is a valuable postbiotic ingredient, demonstrating clinical efficacy in reducing acne and supporting a balanced skin microbiome with a low risk of irritation, making it highly suitable for targeted skincare formulations.


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