Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

ECHINACEA PURPUREA LEAF/STEM/MERISTEM CELL CULTURE EXTRACT.

Valuable CAS 90028-20-9 / SKIN CONDITIONING

This advanced cellular extract from Echinacea purpurea offers a multi-faceted approach to skin health, delivering potent antioxidant protection and significant anti-inflammatory benefits. It clinically enhances hydration and improves the epidermal barrier, contributing to a more resilient and youthful complexion. Its comprehensive action targets environmental damage, irritation, and signs of aging.

Summary

Antioxidant Anti-inflammatory Barrier Support Hydrating Anti-aging Wound Healing Support Soothing Antimicrobial

Science

Mechanism of Action

ECHINACEA PURPUREA LEAF/STEM/MERISTEM CELL CULTURE EXTRACT functions as a powerful antioxidant, actively neutralizing free radicals to shield the skin from environmental stressors and decelerate photoaging. Its anti-inflammatory action is achieved by modulating nitric oxide (NO) activities and various cytokine pathways, effectively calming irritation and reducing redness. This extract significantly reinforces the skin's intrinsic defense systems and optimizes the epidermal lipid barrier, leading to improved skin hydration and a visible reduction in wrinkle depth. Moreover, it exhibits in vitro wound healing capabilities and possesses antimicrobial properties, primarily attributed to its rich content of caffeic acid derivatives such as echinacoside.

Research

Clinical Evidence

Medium confidence
Effective range 50–200%
Optimal

N/A

Key findings

  1. 01 Clinical trials have shown that Echinacea purpurea extracts, particularly a root extract formulated in a water/oil emulsion, provide anti-inflammatory effects and enhance the epidermal lipid barrier, effectively soothing skin complaints in patients with atopic dermatitis.
  2. 02 In a study with 10 healthy volunteers aged 25-40 years, topical application of Echinacea purpurea cream and gel over one month led to a notable increase in skin hydration, with corneometer indices rising by up to 11.4 AU, and a reduction in wrinkle depth by as much as 14.92%.
  3. 03 In vitro scratch tests on human dermal fibroblasts (NHDF) demonstrated wound healing potential and maintained cell viability with Echinaceae purpureae folium (EPF) extract at concentrations ranging from 50 to 200 µg/mL.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 6 – 6
0 7 14

Stability

The extract exhibits low stability when exposed to atmospheric air due to oxidation and is sensitive to higher temperatures. Optimal stability is achieved around pH 6.00, as this minimizes the rate of hydrolysis. Stability can be significantly improved by the inclusion of α-tocopherol or disodium editate, and by formulation in aqueous solutions containing solvents such as ethanol, propylene glycol, glycerol, or sorbitol. Degradation of alkamides is faster in dry films compared to DMSO solutions, although phenolic acids can help mitigate alkamide loss in dry extracts.

Synergies

  • α-tocopherol
  • disodium editate
  • ethanol
  • propylene glycol
  • glycerol
  • sorbitol

Conflicts

  • sugar

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

Echinacea Purpurea Extract is affirmed as safe for cosmetic applications by the CIR. It is non-irritating and displays no cytotoxicity. While generally well-tolerated, individuals with known allergies to plants in the Asteraceae family (e.g., ragweed, marigolds) should exercise caution. Adverse effects reported with internal use of general Echinacea preparations (e.g., abdominal pain, rash) are not typically observed with its topical cosmetic application.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

ECHINACEA PURPUREA LEAF/STEM/MERISTEM CELL CULTURE EXTRACT is a valuable botanical ingredient, clinically shown to enhance skin hydration, reduce wrinkles, and provide significant anti-inflammatory and antioxidant benefits, particularly suitable for sensitive and compromised skin.

Related

Similar Ingredients

Finding similar ingredients…