Science
Mechanism of Action
As a cationic QAC, Ditallowdimonium Chloride is substantive, meaning it binds to negatively charged surfaces like hair and skin, which contributes to its antistatic and conditioning properties. It also functions as a surfactant to reduce surface tension and as an emulsifier to stabilize immiscible liquids. Related QACs are understood to potentially interact with and disrupt cellular lipid bilayers and denature proteins.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
No specific optimal pH range for Ditallowdimonium Chloride stability has been established. It exhibits very low solubility in water (approximately 3.24e-008 mg/L at 25°C), classifying it as practically insoluble, but demonstrates high solubility in organic solvents.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not conducted a specific safety assessment for Ditallowdimonium Chloride (also known as Quaternium-48). While some related quaternary ammonium compounds, such as Quaternium-15, have been deemed safe as non-sensitizers up to 0.2%, these conclusions do not directly apply to Ditallowdimonium Chloride. FDA regulations for related QACs typically pertain to disinfectant applications on food-contact surfaces, which is distinct from cosmetic skincare use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Due to a lack of specific CIR safety review, unknown irritancy/comedogenicity, and no clear skin-specific clinical data, Ditallowdimonium Chloride has insufficient data to warrant inclusion in precision skincare formulations.
Related
Similar Ingredients
Finding similar ingredients…