Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

DISODIUM PHOSPHOCREATINE.

Valuable CAS 922-32-7 / SKIN CONDITIONING

Disodium Phosphocreatine is a high-energy phosphate compound designed to bolster cellular energy reserves by regenerating ATP, especially when skin experiences metabolic stress. This critical energy supply supports significant skin health benefits, including enhanced antioxidant activity, protection against UV-induced damage, and improved repair mechanisms.

Summary

antioxidant skin conditioning

Science

Mechanism of Action

At a cellular level, Disodium Phosphocreatine functions as an essential energy buffer, restoring adenosine triphosphate (ATP) reserves through the action of creatine phosphokinase enzymes. This process is particularly vital during periods of metabolic stress or ischemia, where energy demands are high. For the skin, this translates into fortified antioxidant defenses to mitigate oxidative stress, robust protection against UV radiation, and documented efficacy in reversing photodamage and accelerating the natural wound healing process.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 8 – 12
0 7 14

Stability

While phosphocreatine is generally unstable in aqueous solutions, the disodium salt form provides enhanced water solubility and improved stability. Pharmaceutical compositions containing Disodium Phosphocreatine demonstrate optimal stability within a pH range of 8.0 to 12.0. For best potency, solutions prepared for use should ideally be consumed on the same day or stored at -20°C for up to one month.

Conflicts

  • strong oxidizers

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Disodium Phosphocreatine has not undergone specific evaluation by the Cosmetic Ingredient Review (CIR) Expert Panel. Although the CIR Panel reviewed related compounds (Phosphoric Acid and its salts, including Disodium Phosphate) and deemed them safe when formulated to be non-irritating, this assessment does not directly apply to Disodium Phosphocreatine. No specific safety status has been established by the SCCS or FDA for its cosmetic use. While Safety Data Sheets for its tetrahydrate form suggest no known effects from normal skin contact or ingestion, listings for the raw chemical indicate potential for skin and serious eye irritation.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Disodium Phosphocreatine offers valuable potential in precision skincare due to its fundamental role in cellular energy and its demonstrated antioxidant, UV protective, and regenerative skin benefits.

Related

Similar Ingredients

Finding similar ingredients…