Science
Mechanism of Action
As a member of the alkyl polyethylene glycol sulfosuccinate family, this ingredient functions primarily as a surfactant by effectively lowering the surface tension of the stratum corneum, which facilitates the removal of dirt and impurities from both skin and hair. Beyond cleansing, it boosts foam volume and stability, acts as a hydrotrope to increase the water solubility of other substances, and can serve as an emulsifier and dispersant to combine immiscible phases like oil and water.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Clinical patch tests on a closely related ingredient, Disodium Laureth Sulfosuccinate, at concentrations of 5% and 10% in aqueous solutions, demonstrated no skin irritation in healthy subjects or those with pre-existing dermatitis.
- 02 A commercial formulation containing 1.68% active Disodium Laureth Sulfosuccinate was found not to induce clinically significant irritation or any evidence of allergic contact dermatitis in normal human subjects.
- 03 It is important to note that while aqueous solutions were non-irritating, a 10% concentration of the related ingredient in a citrate buffer was classified as a mild skin irritant, underscoring the critical role of overall product formulation in mitigating irritation.
Transparency
Dusting Analysis
No data available specifically concerning 'dusting' or minimal effective concentrations for primary therapeutic outcomes for this ingredient.
The Formula
Formulation
Stability
This sulfosuccinate ingredient, owing to its ester linkage, is sensitive to hydrolysis, particularly under highly acidic conditions. It maintains stability in hard water and generally performs best within a near-neutral to slightly acidic pH range of 5.0 to 7.0.
Conflicts
- Highly acidic conditions (potential for hydrolysis)
- High concentrations of oils or fragrances (requires additional solubilizers like polysorbates if exceeding approximately 3% concentration)
- Thickening with sodium chloride (does not respond to salt thickening and necessitates alternative thickeners such as Crothix or various gel-forming agents)
Safety
Safety Profile
The CIR Expert Panel has concluded that alkyl PEG sulfosuccinates, including Disodium Deceth-5 Sulfosuccinate, are safe for use in present cosmetic practices and concentrations when formulated to be non-irritating. There is a potential for ocular and/or skin irritation if the product is not formulated appropriately to mitigate this risk. This ingredient was reported to the FDA's Voluntary Cosmetic Registration Program (VCRP) in 2011.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Disodium Deceth-5 Sulfosuccinate is a valuable, mild surfactant and cleansing agent, broadly compatible with all skin types when correctly formulated to ensure a non-irritating profile.
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