Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

DIPROPYLENE GLYCOL.

Valuable CAS 110-98-5 / 25265-71-8 / FRAGRANCE, PERFUMING, SOLVENT, VISCOSITY CONTROLLING

Dipropylene Glycol is a multifaceted ingredient valued for its hydrating properties, ability to dissolve a wide range of compounds, and its role in enhancing the delivery of active ingredients into the skin. It contributes significantly to product texture and overall formulation stability.

Summary

Humectant Solvent Permeation Enhancer Viscosity Controlling Masking Agent Perfuming (Fragrance Carrier/Fixative) Product Stabilizer

Science

Mechanism of Action

Functioning as a humectant, Dipropylene Glycol actively draws and retains moisture, effectively alleviating dryness and supporting skin hydration. Its robust solvent capabilities allow it to effectively dissolve both water-soluble and oil-soluble ingredients, ensuring homogenous distribution of active compounds and pigments within formulations. Additionally, it acts as a chemical permeation enhancer, subtly modifying the stratum corneum to facilitate deeper penetration of co-formulated active ingredients. It also serves to decrease viscosity for optimal texture and spreadability, masks undesirable odors, and stabilizes products against temperature and pH fluctuations.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

10%

Key findings

  1. 01 The SCCS (Scientific Committee on Consumer Safety) confirmed Dipropylene Glycol is safe for use in leave-on cosmetic products at concentrations up to 10%.
  2. 02 The SCCS also found it safe for use in rinse-off cosmetic products at concentrations up to 50%.
  3. 03 The CIR Expert Panel demonstrated an absence of dermal sensitization at typical use concentrations.
  4. 04 Toxicological studies reviewed by SCCS indicate low acute toxicity and no evidence of skin irritation or sensitization.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Dipropylene Glycol is completely miscible in water and many organic solvents, including oils, which enhances ingredient dispersion. It effectively stabilizes formulations against variations in temperature and pH. Given its hygroscopic nature, proper storage involves protection from humidity and temperatures should not exceed 40°C (104°F) to maintain integrity.

Synergies

  • Enhances the penetration and efficacy of other active ingredients by improving their solubility and facilitating deeper skin delivery.
  • Serves as an effective carrier and fixative for fragrances due to its mild odor and slow evaporation rate.

Conflicts

  • Should not be incorporated into candle bases of any type due to its high flame potential.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
10%
Sensitization risk Low

The CIR Expert Panel concluded Dipropylene Glycol is safe when used in cosmetic formulations that are nonirritating. The SCCS affirmed its safety at concentrations up to 10% for leave-on products and 50% for rinse-off products. The FDA permits its use as an indirect food additive. It exhibits low acute toxicity across oral, dermal, and inhalation routes, and has shown no evidence of carcinogenicity, genotoxicity, or adverse effects on fertility or reproduction. While generally well-tolerated, a small subset of individuals may experience contact dermatitis, particularly with higher concentrations or prolonged exposure.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Dipropylene Glycol is a highly valuable component in precision skincare formulations due to its robust safety profile and versatile functionality as a humectant, solvent, and permeation enhancer, suitable for all skin types.

Related

Similar Ingredients

Finding similar ingredients…