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DIPEPTIDE-19.

Insufficient Data / SKIN CONDITIONING

DIPEPTIDE-19 is a synthetic peptide typically integrated into larger, multi-peptide complexes rather than appearing as a standalone ingredient in skincare formulations. While specific individual research is limited, its presence in these advanced complexes suggests potential contributions to skin revitalization and repair.

Skin conditioning Anti-aging agent Anti-wrinkle agent Skin-lifting agent Wound healing agent

Science

The precise mechanism of DIPEPTIDE-19 in isolation is not extensively documented. However, when incorporated into fusion peptides like SH-OLIGOPEPTIDE-1 SH-POLYPEPTIDE-7 DIPEPTIDE-19, it is associated with a range of beneficial skin activities. These include promoting anti-wrinkle effects, enhancing skin firmness and lifting, supporting wound healing processes, and contributing to overall anti-aging cellular functions within the skin.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 7 – 7.4
0 7 14

Stability

As with many peptides, DIPEPTIDE-19 is susceptible to various forms of degradation, including hydrolysis, oxidation, deamidation, and racemization, as well as physical instabilities like aggregation. Optimal stability is significantly influenced by the formulation's pH, temperature, exposure to light, and the presence of metal ions or peroxide contaminants. For related fusion peptides containing DIPEPTIDE-19, an optimal stability range is observed between pH 7.0 and 7.4, with a noted optimum around pH 7.2.

Synergies

  • Other peptides in fusion complexes (e.g., SH-OLIGOPEPTIDE-1, SH-POLYPEPTIDE-7)

Conflicts

  • Extreme pH environments (outside 7.0-7.4)
  • High temperatures
  • UV light exposure
  • Presence of metal ions or peroxide contaminants

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

DIPEPTIDE-19 has not undergone specific safety assessment by the Cosmetic Ingredient Review (CIR) panel or the SCCS. While a peptide referred to as 'Pep19' has achieved Generally Recognized as Safe (GRAS) status for oral consumption up to 3.8 grams per day for body fat reduction, this designation is not directly applicable to the topical cosmetic use of DIPEPTIDE-19 or its derivatives. Comprehensive topical safety data for DIPEPTIDE-19 specifically in cosmetics is currently unavailable.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

DIPEPTIDE-19's precise benefits and safety as a standalone ingredient require further specific research, as current data primarily positions it as a component within larger, multi-peptide complexes.


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